WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:
Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway       Name:Spliceosome       ID:03040
C=127; O=13; E=0.13; R=102.66; rawP=2.26e-23; adjP=9.04e-23
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000131876 NA SNRPA1 small nuclear ribonucleoprotein polypeptide A' 6627 ENSG00000131876
2  ENSG00000134186 NA PRPF38B PRP38 pre-mRNA processing factor 38 (yeast) domain containing B 55119 ENSG00000134186
3  ENSG00000161547 NA SRSF2 serine/arginine-rich splicing factor 2 6427 ENSG00000161547
4  ENSG00000183684 NA ALYREF Aly/REF export factor 10189 ENSG00000183684
5  ENSG00000160201 NA U2AF1 U2 small nuclear RNA auxiliary factor 1 7307 ENSG00000160201
6  ENSG00000115875 NA SRSF7 serine/arginine-rich splicing factor 7 6432 ENSG00000115875
7  ENSG00000136527 NA TRA2B transformer 2 beta homolog (Drosophila) 6434 ENSG00000136527
8  ENSG00000128534 NA NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit 51691 ENSG00000128534
9  ENSG00000108654 NA DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 1655 ENSG00000108654
10  ENSG00000112081 NA SRSF3 serine/arginine-rich splicing factor 3 6428 ENSG00000112081
11  ENSG00000170144 NA HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 220988 ENSG00000170144
12  ENSG00000188529 NA SRSF10 serine/arginine-rich splicing factor 10 10772 ENSG00000188529
13  ENSG00000136450 NA SRSF1 serine/arginine-rich splicing factor 1 6426 ENSG00000136450


Database:KEGG pathway       Name:RNA degradation       ID:03018
C=71; O=3; E=0.07; R=42.38; rawP=5.03e-05; adjP=0.0001
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000144580 NA RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe) 9125 ENSG00000144580
2  ENSG00000128534 NA NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit 51691 ENSG00000128534
3  ENSG00000140395 NA WDR61 WD repeat domain 61 80349 ENSG00000140395


Database:KEGG pathway       Name:Ribosome       ID:03010
C=92; O=3; E=0.09; R=32.71; rawP=0.0001; adjP=0.0001
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000265681 NA RPL17 ribosomal protein L17 6139 ENSG00000265681 ENSG00000215472
2  ENSG00000197728 NA RPS26 ribosomal protein S26 6231 ENSG00000197728
3  ENSG00000122026 NA RPL21 ribosomal protein L21 6144 ENSG00000122026


Database:KEGG pathway       Name:Metabolic pathways       ID:01100
C=1130; O=3; E=1.13; R=2.66; rawP=0.1025; adjP=0.1025
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000108786 NA HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 3292 ENSG00000108786
2  ENSG00000183696 NA UPP1 uridine phosphorylase 1 7378 ENSG00000183696
3  ENSG00000186104 NA CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 120227 ENSG00000186104




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).